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Mitochondrial lipid peroxides and antioxidant enzymes in the liver following phorone-induced glutathione depletion . (Mehmetcik, G.)
Bibliographical information (record 270259)
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Mitochondrial lipid peroxides and antioxidant enzymes in the liver following phorone-induced glutathione depletion .
Author:
 Mehmetcik, G. Search Author in Amazon Books

Publisher:
PJD Pub.,
Edition:
 1997.
Classification:
 QV 4
Detailed notes
    - The levels of lipid peroxidation product (malondialdehyde = MDA) vitamin C and the activities of glutathione peroxidase (GSH-Px) dismutase (SOD) were determined in the liver and its mitochondrial fraction, in the rats 2 and 18 hr after the injection of phorone, a glutathione (GSH) depleting agent. GSH levels decreased in liver homogenate and its mitochondrial fraction after 2 hr of phorone treatment, but these values returned to normal levels at 18 hr. In GSH depleted conditions, hepatic vitamin C levels increased, GSH-Px and SOD activities remained unchanged in mitochondrial and post-mitochondrial fractions. These results indicate that GSH depletion per se does not influence lipid peroxidation and GSH-Px and SOD activities in the liver and the mitochondrial fraction.
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Status
Library
Section
EOL-1769
Item available
NEU Grand LibraryOnline (QV 4 .M58 1997)
Online electronic
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